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How Cannabis Science May Save 10000 UK Prostate Cancer Sufferers A Year
http://pr.cannazine.co.uk : The most common cancer amongst British men is Prostate Cancer. Each year the condition accounts for nearly 35,000 new cases and around 10,000 deaths, with few treatments available for advanced disease. Those which are available are generally palliative in nature, rather than actually dealing with curing the disease itself.
But two cancer patients from the US have defied pharmaceutical logic by surviving the disease with an experimental drug which took advanced prostate cancer (one patient had a tumor said to be the size of a golf ball), and receeded it to such a degree the consultant had to double check he was looking at the right patient notes.
If it all sounds a bit like a science fiction story with a happy ending, thats because its been written by a Public Relations department within a large marketing company.
Doubtless the PR account holders for Bristol-Myers Squibb and Medarex, the two companies involved with the production of the new drug which is turning heads around the world; Ipilimumab.
Ipilimumab, (also known as MDX-010 or MDX-101) is a human monoclonal antibody being developed jointly, by Bristol-Myers Squibb and Medarex.
It is intended to be used as a drug to activate the immune system. Ipilimumab is currently undergoing clinical trials for the treatment of melanoma and other cancers.
But the big clue in all this is how the new drug works.
Ipilimumab is a fully human antibody that binds to CTLA-4 (cytotoxic T lymphocyte-associated antigen 4), a molecule on T-cells that is believed to play a critical role in regulating natural immune responses. The absence or presence of CTLA-4 can augment or suppress the immune system's T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells.
In laymans terms, rather than trying to bombard the cancer with highly toxic and aggressive radiation and chemotherapy treatments which work by physically poisoning, and killing the cancer cells, (but which do not differentiate between healthy cells and cancerous, hence the vigorous and dangerous side-effects), this drug works on boosting the human immune system, and in doing so it gives the human body the tools it needs to deal with the disease itself.
'Organic medicine' if you will, and when we remember the immune system is dealing with, and disposing of dangerous cancer cells on a daily basis, its not hard to see the logic behind this treatment.
Dr Robert Melamede Ph.D. is the former chairman of the Biology Department at UC, (University of Colorado). Dr Melamede has dedicated his life to learning more on how the human cannabinoid system works.
In the text below Dr Melamede gives 20 good reasons why we should look after our immune system, and why (and how) cannabis can help us do it;
Food and feeding is at the heart of the Cannabinoid System.
1. Cannabinoids are in every living animal on the planet above Hydra and Mollusks, with the exception of insects. Bodies are homeostatically maintained by the Cannabinoid System.
2. Mothers give their babies a booster shot of cannabinoids in mothers milk to give them the munchies because they have to learn to eat. (they've been fed thru the umbilical cord and did not have to know how to eat.)
3. Mice lacking the CB1 receptors don't like any changes. If they are moved to another part of the cage they act upset and when they are put back to the original spot in the cage they relax, but if then put into another part of the cage they get upset again. Comment: I wonder if people, especially drug warriors, had their CB1 receptors blocked then they would resist change and the ones of us that have unblocked CB1 receptors enjoy the benefits of cannabinoids are a lot more relaxed and not paranoid about or over change. Interesting thought. It turns out that that thought is absolutely correct. Many people' brains are not capable of a good connection to the CB1 CB2 receptors.
4. All new species utilize cannabinoids.
5. By being alive and breathing air our bodies produce "free radicals". Cannabinoids help to reverse this action.
6. Cannabinoids do kill brain cells, but the brain cells they kill are called "Glioma" or Cancer of the brain(Tumor). All other brain cells are protected and healed by cannabinoids. (Glioma cells cannot tolerate the action of cannabinoids)
7. Cannabinoids protect against sunburn and skin cancer because of the CB1 receptors in our skin.
8. Cannabinoids slow down the aging process. Mice, when responding to cannabinoids were found to live longer, and mice that have brains which block the CB1 receptors, die younger.
9. Activity in the evolutionary advanced areas of the brain is increased in cannabinoids receptors and promotes higher consciousness levels.
10. Cannabinoids are even found in the white blood cells (CB2 receptors). The CB2 receptors are found predominantly on immunological cells and regulate the shift in the immune system to the anti-inflammatory mode.
11. Cannabinoids protect the heart against Arythmia.
12. The way it works on pain is there is specific nerves that deal with pain. They are called vanilloid-Receptors. Anandamide(sanscript word for "Blissful Amide"), the bodies internally produced marijuana binds with the nerve endings, reducing pain. Anandamides are produced internally by our bodies in response to a whole variety of conditions. As an example, Aspirin prevents the breakdown of Anandamide, the internally produced marijuana to activate & start working at easing pain. How many old lady's say they "WOULD NEVER" use marijuana & are actually using the equivalent of marijuana that their bodies produce as a natural activity, & don't even realize it. And how many politicians and citizens of the US do this also & aren't even aware they are condemning something that their bodies make naturally. Anecdotal evidence is valid because when a person smokes marijuana & it relieves their pain, then they smoke it again & it relieves their pain again it becomes a fact known only to that person, but nonetheless true.
13. In the case of most autoimmune diseases, the bodies immune cells produces free radicals & is destroying it's own body as a foreign object. Cannabis pushes the immune system into anti inflammatory mode & helps slow the progression of that disease, thereby slowing down the aging process.
14. Seizures are controlled by marijuana not only THC, but non-psychoactive cannabidiol.(CBD) The exact mechanism is not known, however HEMP is high in CBD's & can cancel out the psychoactive high of THC & at the same time benefits the user or smoker. Cannabinoids control everything in our bodies including our minds.
15. There are many other things that Cannabinoids do in the body, besides attaching to the CB1 and CB2 receptors, the main cannabinoid receptors in the higher part of our brain. Cannabinoids affect our skin and other parts of our bodies.
16. Pharmaceutical companies are working at sythesizing different cannabinoid components and different types of strains of marijuana. If they can succeed, then there will be more choices for you and I to choose from and we will be able to use what works best for our particular bodies.
17. The natural course for mankind, because of the location of our CB1 CB2 the brains main receptors, is to be more stoned.
18. Drug warriors are not doing what they are doing to us because they are intentionally evil, but because they are more primitive (obtuse comes to mind). They look at the world with fear and hostility not cooperativity and understanding.
19. According to a brain function study of 150 depressed people Cannabis protects the brain against healthy cell death and it also protects Neurons.
20. Cannabinoids dilate our brochial tubes and help asthsma sufferers to breath both in and out. Because of the balance that is maintained in our bodies for good health there are instances where it works backwards, where death is possible, if too much is smoked. This goes back to the effects of cannabinoids on individuals and if it doesn't work for you, you should not use it.
There were some old studies that were done back in 1977 where "AEROSOLIZED THC" was used on patients. This is not what the government tells us when they say it's not medicine, but we are all familiar with the 7 government patients that are supplied marijuana to be used as medicine. So why try to tell us otherwise?
In summing up its a most frustrating occurrence when a pharmaceutical giant announces to the world its research points to a cure for cancer. A disease which 1 in 3 of us will deal with at some stage in our lives. Especially when they have done nothing more than concoct a 'broth' to do a job cannabis has been doing for 10,000 years plus.
The fact is by boosting the human immune system using the actual components and circuitry the human body is designed to interact with (the cannabinoid system) we can do it more efficiently, with less side-effects, by using cannabis instead of the many pharmaceutical drugs we're prescribed.
And you wondered why cannabis is illegal?
Dr Melamede explains EXACTLY how the cannabinoid system, (and cannabis) can help us stay happy and healthy.
Wow! So much nonsense in so few words. I laughed really loud reading gems such as:
"Bodies are homeostatically maintained by the Cannabinoid System"
"...against healthy cell death and it also protects Neurons." (those mystical non-cells called Neurons)
"The fact is by boosting the human immune system using the actual ..."
but
"The CB2 receptors are found predominantly on immunological cells and regulate the shift in the immune system to the anti-inflammatory mode."
You demonstrate profound lack of understanding... It will be nice if people like you become of aware of the fact there is no drug/compound/miracle mixture that cures-it-all. Except for the guillotine I am told, but I believe that is not what we are looking for .
As much as I dislike the "drug warriors" as you call them, this pseudo-science exercise does not serve your cause.
I have advanced, agressive, high grade (gleason 9)Prostate Cancer which has now spread to my spine (T10).
The clock is ticking.
I don't smoke. Would cannabis cake work? Can it be taken in any other form?
Please help.
Green/Eco/Environment 
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